Search on: PROTEASE NEXINS 
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Descriptor English:   Protease Nexins 
Descriptor Spanish:   Nexinas de Proteasas 
Descriptor Portuguese:   Nexinas de Proteases 
Tree Number:   D12.644.822.468
D12.776.645.468
Definition English:   Extracellular protease inhibitors that are secreted from FIBROBLASTS. They form a covalent complex with SERINE PROTEASES and can mediate their cellular internalization and degradation. 
History Note English:   2011 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   54058 
Unique Identifier:   D058255 

Occurrence in VHL:
 

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